Hoffman Lab

QUANTITATIVE LUNG IMAGING

Assessment of lung in smoking related diseases
Characterization of anatomic structure and linking to functional behavior
Population studies, clustering, phenotyping
Measurement of mucocilliary clearance in CF
Detection and characterization of cancer
7T MRI, Iowa Biomedical Imaging Institute

NOVEL IMAGING METHODS

Dual energy CT
Micro-CT
PET-CT
MRI (3T, 7T)
Hyperpolarized 129-Xe MRI
Fluorine MRI
Small animal imaging (Micro-CT, MR (7T), PET, SPECT, Ultrasound, OCT)
MR linac
Hoffman Lab

IMAGE ANALYSIS, IMAGING PROCESSING, AND BIG DATA PROCESSING

Segmentation
Registration
Disease detection and staging
Clustering
Deep learning
Robust pipelines for large-scale clinical trials
Microfluidics Lab

COMPUTATIONAL MODELING

►Computational fluid dynamics
►Tissue biomechanics
►Structure-function relationships
►High-frequency and multi-frequency ventilation
►Aerosol deposition and drug delivery
►Radiation therapy planning and treatment monitoring