![Hoffman Lab](/sites/lungimaging.sites.uiowa.edu/files/styles/widescreen__1024_x_576/public/2021-03/Screen%20Shot%202019-02-25%20at%2012.00.27%20PM.png?h=b39a9239&itok=gg7lX74n)
QUANTITATIVE LUNG IMAGING
►Assessment of lung in smoking related diseases
►Characterization of anatomic structure and linking to functional behavior
►Population studies, clustering, phenotyping
►Measurement of mucocilliary clearance in CF
►Detection and characterization of cancer
![7T MRI, Iowa Biomedical Imaging Institute](/sites/lungimaging.sites.uiowa.edu/files/styles/widescreen__1024_x_576/public/2021-03/7T1.jpg?h=3d668d41&itok=PiD6npam)
NOVEL IMAGING METHODS
►Dual energy CT
►Micro-CT
►PET-CT
►MRI (3T, 7T)
►Hyperpolarized 129-Xe MRI
►Fluorine MRI
►Small animal imaging (Micro-CT, MR (7T), PET, SPECT, Ultrasound, OCT)
►MR linac
![Hoffman Lab](/sites/lungimaging.sites.uiowa.edu/files/styles/widescreen__1024_x_576/public/2021-03/dectpbv.jpg?h=b6017305&itok=L4tpjhEJ)
IMAGE ANALYSIS, IMAGING PROCESSING, AND BIG DATA PROCESSING
►Segmentation
►Registration
►Disease detection and staging
►Clustering
►Deep learning
►Robust pipelines for large-scale clinical trials
COMPUTATIONAL MODELING
►Computational fluid dynamics
►Tissue biomechanics
►Structure-function relationships
►High-frequency and multi-frequency ventilation
►Aerosol deposition and drug delivery
►Radiation therapy planning and treatment monitoring